THAP1 |
THAP11 |
CG4201 |
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[Thanatos-associated protein 5; THAP domain containing 5] THAP5 is a human gene that is a member of a family of proteins containing a THAP domain (Roussigne et al, 2003). There is no mouse or rat ortholog (Clouaire et al, 2005; Quesneville et al, 2005).
THAP5 is a tissue-specific nuclear factor that is expressed predominantly in the human heart and at very low levels in human brain and muscle (Balakrishnan et al, 2009). THAP5 is a specific interactor and substrate of the pro-apoptotic mitochondrial serine protease Omi (HtrA2 [HTRA serine peptidase 2]) in cells
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