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TMD2

This lymphoblastoid cell line has been established from the peripheral blood of a patient with chronic lymphocytic leukemia in the acute phase after continuous culture in the presence of IL3. TMD2 cells depend on the presence of IL3. Other factors, including IL1, IL2, IL4, IL5, IL6, GM-CSF, G-CSF, or SCF do not support the growth or survival of TMD2 cells. Antibodies against IL3 block the stimulatory effect of IL3 on these cells.

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