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serum spreading factor

abbr. SF. Human serum spreading factor is a blood glycoprotein. Two native forms are seen in human serum (SF65, 65 kDa and SF75, 75 kDa) (Barnes and Silnutzer, 1983).

Serum spreading factor promotes attachment and spreading and influences growth, migration, and differentiation of a variety of animal cells in culture (Barnes et al, 1980) (see also: motogenic cytokines). The use of monoclonal antibodies has shown that serum spreading factor is present also at the cell surface and in tissues. Basara et al (1985) have reported that Serum spreading factor stimulates haptotaxis in a variety of cell types (including epithelial cells, fibroblastic cells ... ... ... ... ... Subscribe to continue reading! ... ...

 

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