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FDCR-1

[FDC-derived receptor-1] This is a member of the TNF receptor superfamily cloned from FDC-1 cells (resembling follicular dendritic cells). FDCR-1 is identical with OPG (osteoprotegerin).

FDCR-1 is a receptor for RANKL (TRANCE). FDCR-1 is membrane-bound on the surface of FDC-1 cells. It is expressed in lymphoid cells and its expression is upregulated by CD40 stimulation.

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