GDF16 |
GDGF-1 |
DIF |
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[Glioma-derived growth factor] One specific factor, designated GDGF-1, is a homodimer of a protein structurally closely related to the A-chain of PDGF. This PDGF-related factor also binds to the same receptors as PDGF-A.
In contrast to PDGF GDGF-1 shows a reduced mitogenic activity. It only stimulates weakly the autophosphorylation of its receptor and does not possess chemotactic activities (see also: Chemotaxis). GDGF-1 modulates the expression of the receptor for EGF (see also: Receptor transmodulation).
The factor known as GDGF-2
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