gp34

The expression of this cellular protein is induced in cells harbouring human T-cell leukemia virus type I (HTLV-I) (Miura et al, 1991). The protein is known also as TXGP1 [tax-transcriptionally activated glycoprotein 1]. gp34 is a type 2 transmembrane protein that is produced relatively late during infection. Its synthesis is induced by, and depends on, the viral tax protein. The protein is a member of the TNF ligand superfamily of proteins.

Nakamura et al (1997) have reported that normal T-cell transiently express both gp34 and the receptor for gp34, OX40, upon antigenic stimulation.

Godfrey et al (1994) have cloned the same gene and identified gp34 as the human ... ... ... ...
 
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