transgenic

The term "transgenic " describes organisms that contain in their chromosomes stably integrated copies of genes or gene constructs derived from other species or not normally found in the host animals. These so-called transgenes may or may not be expressed. Transgenic animals have been generated for many species and can be generated by introducing cloned DNA of the foreign genes into fertilized oocytes by micro-injection into pronuclei. These oocytes are subsequently transferred into the uterus of a pseudo-pregnant recipient animal and develop to term. Another strategy involves the use of embryonic stem cells (see: ES cells). These cells ... ... ... ...
 
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Entry last modified: November 2005