CTLL-2

A murine cytotoxic T-cell line derived from C57/Bl/6 inbred mice. The cells have been shown to secrete Serglycin into the conditioned medium.

CTLL-2 cells constitutively express IL2 receptors and depends entirely on the presence of IL2 for its growth (see also: Factor-dependent cell lines). It is used in bioassays of this factor (see also: cytokine assays). The cells appear to be capable of growing on a matrix containing immobilized IL2.

The activity of IL2 is determined by measuring the incorporation of tritiated thymidine into the newly synthesized DNA ... ... ... ...
 
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Entry last modified: December 2007