Cytokine IK |
cytokine-independent survival kinase |
Cytokine Concentrations in Biological Fluids |
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abbr. CITA. This immunoassay allows determination of the rate of production of cytokines under conditions that prevent consumption/degradation (see also: bioassays, cytokine assays).
Cytokines secreted during cell culture are captured early by polystyrene macrobeads coated with monoclonal antibodies or by soluble antibodies and detected by a chemiluminescent immunoassay employing a second cytokine-specific antibody.
The assay has been established for the detection of IFN-gamma and is also suitable for the early detection of IL1 and IL4. Under optimal conditions IFN-gamma concentrations
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