PC-4

[pheochromocytoma cell-4] An early response gene the transcription of which is stimulated rapidly and transiently by treatment of cells with mitogens or agents that induce differentiation (Jahner and Hunter, 1991; Kreider and Rovera, 1992). PC-4 expression is induced by treatment of cells with Phorbol esters such as 12-O-tetradecanoyl-phorbol-13-acetate. PC-4 is expressed at high levels along the whole neural tube of early rat embryos (Iacopetti et al, 1996).

The rat PC-4 gene has been isolated as an NGF inducible sequence in PC12 cells during the course of neuronal differentiation. PC-4 is identical with ... ... ... ...
 
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Entry last modified: January 2015