foreign body reaction
The foreign body reaction is an inflammatory reaction of the body elicited in response to implanted biomaterials and is of great importance for the function and turnover of biomaterial scaffolds. It is regulated by soluble mediators produced locally by tissue cells and infiltrated inflammatory cells. These mediators include cytokines, chemokines, growth factors, other bioactive agents, and matrix metalloproteinases. The foreign body reaction involves different cell types, including neutrophils (polymorphonuclear leukocytes), mast cells, monocytes, macrophages, lymphocytes, plasma cells,
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