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BLyS

[B-lymphocyte stimulator] This protein of 285 amino acids is a member of the TNF superfamily of cytokines identified in a human cDNA library derived from neutrophils and monocytes (Schneider et al, 1999). The protein shares 28.7 % identity to APRIL. The human gene maps to chromosome 13q34. BLyS has been given the designation TNFSF13B [TNF ligand superfamily member 13B]. Other names for the protein are BAFF, TALL-1, zTNF4, and THANK.

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