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The MY7 antigen is named after the monoclonal antibody derived from a fusion of the NS-1 plasmacytoma cell line with splenocytes from a mouse immunized with human acute myelomonocytic leukemia cells. MY7 defines a myeloid differentiation antigen in that it is not detected on myeloid precursor cells and appears at discrete stages of differentiation. The antigen is not expressed by lymphocytes, erythrocytes, platelets, or lymphoid malignancies. MY7 is expressed by granulocytes, monocytes, and 5 % of normal bone marrow cells. 79 % of all acute myeloblastic leukemia
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